Advanced Semen analysis

Advanced semen analysis may include an evaluation of sperm DNA fragmentation, which is assessed through a test called the "Sperm DNA Fragmentation Index (DFI) test." This test provides additional insights into male fertility by examining the integrity of the genetic material within sperm.

Here's a brief overview of advanced semen analysis:

• Sperm Vitality: In addition to assessing sperm count, motility, and morphology, advanced semen analysis may include a test for sperm vitality. This test determines the percentage of living sperm in the sample. It helps distinguish between live, healthy sperm and non-viable sperm.
• Sperm Agglutination: Sperm agglutination refers to the clumping or sticking together of sperm. This phenomenon can affect sperm movement and reduce fertility. Advanced testing can identify agglutination and provide information on the extent of the issue.
• Sperm DNA Fragmentation: Advanced analysis can include tests for sperm DNA fragmentation, which measures the integrity of the genetic material within sperm. High levels of DNA fragmentation can be associated with reduced fertility and an increased risk of miscarriage.
• Sperm Antibodies: Some men produce antibodies against their sperm, which can hinder sperm motility and function. Advanced semen analysis can test for the presence of these antibodies.
• White Blood Cells (Leukocytospermia): Elevated levels of white blood cells in semen can indicate infection or inflammation in the male reproductive tract. This can impact sperm quality, and advanced testing may assess white blood cell counts.
• Sperm Capacitation: Capacitation is the process that prepares sperm for fertilization. Advanced analysis may assess the capacitation status of sperm, helping to identify functional sperm with higher fertilization potential.

The Sperm DNA Fragmentation Index test is part of an advanced evaluation of male fertility and provides additional information beyond the standard semen analysis. It can be particularly useful for couples who are facing unexplained infertility or recurrent pregnancy loss and can help guide treatment strategies to improve the chances of successful conception.